MAASTY is a methacrylic acid–styrene copolymer series engineered for direct extraction of membrane proteins into native nanodiscs. Developed at the Autzen lab at University of Copenhagen and the Nanosmithery at DTU Health Tech, and published in Nature Communications, RadPoly makes MAASTY available to researchers worldwide.
MAASTY40 through MAASTY60 span 40–60 mol% methacrylic acid in 5 mol% steps — giving you systematic control over hydrophilic–hydrophobic balance and the ability to find the optimal variant for your membrane protein and lipid system.
Synthesised by reversible addition-fragmentation chain-transfer polymerisation, every MAASTY batch delivers defined molecular weight and verified composition — the same reproducibility your assays demand.
MAASTY nanodiscs retain endogenous lipids — including cholesterol and phosphatidylinositol — giving you a lipid environment that reflects the native membrane rather than a reconstituted approximation.